Online ISSN 2313-1519
Print    ISSN 1812-2892
Abstract - Possibility of influence of hemofiltration in mechanisms of glutamate excitotoxicity in ischemic stroke
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Almagul Zhussupova, Agzam Zhumadilov, Sholpan Nurmanova, Alexander Zlotnik, Askhat Bekmukhanbetov, Marat Abduov, Igor Kim

Currently, much attention has been paid to the value of the presence of biomarkers in blood and cerebrospinal fluid in acute ischemic stroke. The results of experimental studies have shown that an increase in biomarkers particularly glutamate demonstrated high sensitivity and specificity with a positive prognostic value. High levels of glutamate could be regarded as a marker for high risk of development of cerebral tissue infarction. However, the fact that the reduced level of glutamate in the blood of patients with an ischemic stroke might lead to positive results need to be confirmed in further clinical studies.

Volume 4, Number 34 (2014)