Online ISSN 2313-1519
Print    ISSN 1812-2892
Abstract - Impact of renal artery denervation on insulin resistance in patients with resistant hypertension
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Abdurashid Mussayev, Marat Aripov, Serik Alimbayev, Gulnara Zhussupova

The aim: To study the effect of renal artery denervation on blood pressure and insulin resistance in patients with resistant hypertension
Methods: Sixty-three patients underwent denervation of the renal arteries with resistant hypertension. We investigate blood pressure, glucose tolerant test, HOMA-IR and the level of glucose in blood.
Results: It showed a significant reduction in office systolic (-36,1 ± 22,2 mm Hg; P <0.0001) and diastolic (-22,3 ± 14,2 mm Hg; P <0.0001) blood pressure; no statistically significant reduction in glucose tolerant test (6,7 ± 2,5 to 6,1 ± 1,9; P = 0,25). Insulin resistance index fell from an average of 3,0 ± 4,6 baseline to 2,5 ± 3,7 (p = 0.007) at 12 months after denervation of the renal arteries.
Conclusions: renal artery denervation is a safe and effective method of treatment for resistant hypertension, which also has a positive effect on glucose metabolism

Volume 4, Number 38 (2015)