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Abstract - Cryoglobulinemic vasculitis as a rare complication of rheumatoid arthritis : a case report
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Gaukhar Bakhtiyarova, Mehtap Tinazli

ABSTRACT

Cryoglobulinemic vasculitis (CV); is a disease characterized by cryoglobulin-containing immunodeposits that often involve small vessels of the skin and glomeruli. It is considered to be a rare disorder. There are few cases identified in patients with rheumatoid arthritis (RA) suffering from immunological disorders such as Sjogren’s Disease and infectious agents such like as human immunodeficiency virus (HIV) or hepatitis C virus (HCV) infection. We wanted to share a case where we think of cryoglobulinemic vasculitis with rheumatoid arthritis at 50 years old. He applied to us with cyanosis fingertips and severe pain in his hand. Clinical features were assessed by laboratory and nailfold capillaroscopy and CV was diagnosed. Then the patient was treated with intravenous Iloprost for 5 consecutive days, nifedipin and antiagregan. Clinically, the patient presented with a significant reduction of pain and decrease of fingertips ulsers after the second monthly treatment.

Key Words: Cryoglobulinemia; vasculitis; rheumatoid arthritis

 

REFERENCES

1. Makol A, Matteson EL, Warrington KJ. Rheumatoid vasculitis: an update. Curr Opin Rheumatol. 2015; 27(1): 63-70.
https://doi.org/10.1097/BOR.0000000000000126

2. Ferri C, Zignego AL, Pileri SA. Cryoglobulins (review) J Clin Pathol. 2002; 55: 4-13.
https://doi.org/10.1136/jcp.55.1.4

3. Brouet JC, Clouvel JP, Danon F, Klein M, Seligmann M. Biologic and clinical significance of cryoglobulins. Am J Med. 1974; 57: 775-88.
https://doi.org/10.1016/0002-9343(74)90852-3

4. Ferri C. Mixed cryoglobulinemia. Orphanet J Rare Dis. 2008; 3-25.
https://doi.org/10.1186/1750-1172-3-25

5. Sokolovic S, Dervisevic V, Fisekovic S. Mental health status can reflect disease activity in rheumatoid arthritis. Eur J Rheumatol 2014; 1: 55-7.
https://doi.org/10.5152/eurjrheumatol.2014.020

6. Makol A, Crowson CS, Wetter DA, Sokumbi O,Matteson EL, Warrington KJ. Vasculitis associated with rheumatoid arthritis: a case-control study. Rheumatology (Oxford). 2014; 53(5): 890-899.
https://doi.org/10.1093/rheumatology/ket475

7. Turesson CM. Extraarticular features of rheumatoid arthritis and systemic involvement. In: Hochberg MC, et al., editors. Rheumatology. 4th edn. Philadelphia: Mosby; 2008. Pp. 773-83.

8. Scott DG, Bacon PA. Tribe CR. Systemic rheumatoid vasculitis: a clinical and laboratory study of 50 cases. Medicine. 1981; 60:288-9
https://doi.org/10.1097/00005792-198107000-00004

9. Guidelli GM, Bardelli M, Fioravanti A, Selvi E. Nailfold capillaroscopy in Buerger's disease: A useful tool?. Eur J Rheumatol 2014; 1: 81-3.
https://doi.org/10.5152/eurjrheumatol.2014.015

 

Volume 4, Number 46 (2017)