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Abstract - The Platelecrit: The Role in Differential Diagnosis of Small Renal Masses
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Reha Girgin, Önder Cinar, Ersan Bulut, Bulent Akduman, Gökhan Ceker

 

ABSTRACT

Objective: To evaluate the importance of preoperative plateletcrit value predicting malignancy in patients who undergo open surgery due to small renal masses.

Material and methods: Sixty-eight patients who underwent open partial or radical nephrectomy for renal masses were included in this retrospective study. In preoperative routine blood tests, renal ultrasonography and contrast-enhanced computed tomography were performed for all patients. Preoperative plateletcrit values were compared in patients with clear cell renal cell carcinoma (Group 1, 57 patients) and benign lesions (Group 2, 11 patients). The predictive ability of plateletcrit was analyzed by ROC-curves and Youden Index method was used to identify the cut-off value for plateletcrit.

Results: The mean age of patients was 57.33±8.65 years in Group 1 and 59.32±10.59 years in Group 2 (p=0.546). The mean tumor size was 31.1 ± 5.84 mm in Group 1 and 28.07 ±6.25 mm in Group 2 (p=0.132). The median plateletcrit value was 1858,21 ±268,49 in Group 1 and 2258,01±524,35 in Group 2 (p:0.017). The area under a ROC-curve was 0.756 (p<0.05) .

Conclusion: Preoperative plateletcrit values may predict renal masses that can not be distinguished radiologically. Our results must be confirmed by large and properly designed prospective, randomized trials.

Key words: renal cell carcinoma, plateletcrit, platelets, inflammation

 

 Corresponding Author: Reha Girgin, M.D, Department of Urology, Medical Faculty, Bulent Ecevit University, Zonguldak, Turkey. Tel.: 05378865912. E-mail: mujdereha@hotmail.com

 

 

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Volume 2, Number 56 (2020)