A clinical case of pityriasis rubra pilaris - juvenile type

Bahrambek Mukhamedov 1, Evelina Koldarova 2 * , Obid Kurbanov 1
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1 Department of Therapeutic Subjects, Tashkent State Dental Institute, Tashkent, Uzbekistan
2 Dermatology Department, Asmo clinic, Tashkent, Uzbekistan
* Corresponding Author
J CLIN MED KAZ, Volume 20, Issue 3, pp. 115-118. https://doi.org/10.23950/jcmk/13360
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ABSTRACT

Pityriasis rubra pilaris is a rare chronic inflammatory papulo-squamous skin disease, the pathogenesis of which is still unclear. The pathological essence of the disease is associated with a violation of keratinization against the background of hyperactivity of keratinocytes with subsequent inflammation, as well as with vitamin A dysmetabolism and a weakening of the protein-binding fiction of the liver. Unfortunately, treatment is complex with inconsistent improvement from topical therapies, including emollients, keratolytics, corticosteroids, vitamin D analogs, and retinoids. We present a clinical case of the juvenile type of Devergie’s disease in a 3-year-old child, which was caused by poisoning.
Keywords: Pityriasis rubra pilaris, Devergie's disease, juvenile form, systemic retinoids

CITATION

Mukhamedov B, Koldarova E, Kurbanov O. A clinical case of pityriasis rubra pilaris - juvenile type. J CLIN MED KAZ. 2023;20(3):115-8. https://doi.org/10.23950/jcmk/13360

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