Are the type of gastrectomy and the presence of complications prognostic factors in patients with gastric cancer without lymph node involvement?

Orhan Uzun 1 * , Selçuk Gülmez 1, Aziz Serkan Senger 1, Cem Batuhan Ofluoğlu 1, Tolga Olmez 1, Hilmi Bozkurt 1, Erdal Polat 1, Mustafa Duman 1
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1 Gastroenterolgical Surgery Department, University of Health Sciences, Kartal Kosuyolu Higher Specialty Training and Research Hospital, Istanbul, Turkey
* Corresponding Author
J CLIN MED KAZ, Volume 4, Issue 58, pp. 23-27. https://doi.org/10.23950/1812-2892-JCMK-00783
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ABSTRACT

Objective: Lymph node involvement is one of the leading prognostic factors in patients with gastric cancer without distant metastasis, although disease-related death also occurs in patients without lymph node involvement. The present study investigates whether gastrectomy type and complication presence is a prognostic factor in gastric cancer patients without lymph node involvement.
Material and methods: The data of 262 patients who underwent curative gastrectomy at our clinic between November 2006 and December 2018 was reviewed retrospectively.
Results: No lymph node involvement was identified in 33.2% of the patients who underwent curative gastrectomy, and survival in this group was better than in the patient group with lymph node involvement (75.9% vs. 32.6%). A comparison of the two groups revealed significant differences in terms of Borrmann’s classification, Lauren classification, T stage, vascular invasion, perineural invasion, tumor diameter and total number of lymph nodes. Disease-related death occurs also in patients without lymph node involvement, with tumor diameter, T stage, gastrectomy type and the presence of complications all found to be factors affecting the risk of death.
Conclusion: Patients without lymph node involvement have a better prognosis, and aside from tumor diameter and T stage, the present study found gastrectomy type and the presence of complications to be prognostic risk factors.
Keywords: negative lymph nodes, prognostic factors, gastric cancer, overall survival

CITATION

Uzun O, Gülmez S, Senger AS, Ofluoğlu CB, Olmez T, Bozkurt H, et al. Are the type of gastrectomy and the presence of complications prognostic factors in patients with gastric cancer without lymph node involvement?. Journal of Clinical Medicine of Kazakhstan. 2020;4(58):23-7. https://doi.org/10.23950/1812-2892-JCMK-00783

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