CARDIOVASCULAR SYSTEM IN NEWBORNS AND INFANTS WITH CHD, SUFFERED CHRONIC INTRAUTERINE AND / OR PERINATAL HYPOXIA

The aim of this work was to determine the state of the cardiovascular system in newborns and children of early age with the congenital heart defects, who have chronic perinatal and\or perinatal hypoxia.
Material and methods. We examined 83 of the child with the congenital heart defects (1 grp.) and 58 of the children without the congenital heart defects (2 grp.), undergoing chronic prenatal and perinatal hypoxia, as well as a control group of 40 relatively healthy children. We have carried out the clinicalepidemiological analysis of maternal history, as well as the complex examination of children of all 3 groups.
Results. In maternal history revealed the presence of indicators of risk of congenital viral infection in 100% of children with the congenital heart defects (1 grp.) and in 95% of children with postgypoxsical syndrome (2 grp.). In 10 (12%) of the surveyed children with congenital heart defects were observed severe fetal infections. In 40 (83%) of newborns along with the congenital heart defects, there were signs of persistent pulmonary hypertension and functioning of fetal communications. In 66,7% of newborns with congenital heart defects and in 73.7% of children with postgypoxsical syndrome violations of adaptation of cardio-vascular system on 4-5-th day of life was observed delay liquid. In 35,4% of newborns with the congenital heart defects and in 26,3% of children with postgypoxsical syndrome violations of adaptation of cardio-vascular system noted hepatomegaly. Decrease of diastolic blood pressure was observed in all 3 groups. State of the majority of children with the congenital heart defects in using of vasodilators on the background ensure adequate oxygenation (up to artifi cial lung ventilation), correction of metabolic acidosis and metabolic disease progressively improved (by the end of the fi rst week of life). The results of clinical observation during lifetime of children allowed to commit frequent acute respiratory viral infections in the fi rst year of life, including with complicated course in 52.8% of the children with the congenital heart defects and in 60% of children with postgypoxsical syndrome violations of adaptation of cardio-vascular system, pneumonia - in 77% of children with congenital heart defects during the fi rst year of life. Of the congenital heart defects the most common anomalies - the transposition of great vessels, atrial septal defect, an open arterial channel, ventricular septum defect.