Clinical and laboratory COVID-19 features in hospitalized patients with concomitant diabetes mellitus type 2: A retrospective study

Arailym Abilbayeva 1 * , Anel Tarabayeva 1, Gulzhana Idrisova 1, Aigul Abdrakhmanova 2, Ainur Sadykova 3, Ravilya Yegemberdiyeva 3, Amangul Duisenova 3
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1 Department of General Immunology, Asfendiyarov Kazakh National Medical University, Almaty Kazakhstan
2 City Clinical Infectious Diseases Hospital named after I.Zhekenova, Almaty, Kazakhstan
3 Department of Infectious and Tropical Diseases, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
* Corresponding Author
J CLIN MED KAZ, Volume 19, Issue 6, pp. 83-88. https://doi.org/10.23950/jcmk/12719
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ABSTRACT

Objective: To investigate the prevalence of diabetes mellitus in comorbidity structures and its effect on the clinical course in hospitalized COVID-19 patients in south region of Kazakhstan.
Material and methods: A retrospective analysis of data from 918 patients with COVID-19 treated at the City Clinical Infectious Diseases Hospital was carried out. Pearson's Chi-square test and Student's t-test were conducted.
Results: In Kazakhstan, diabetes mellitus occupies the second position in the structure of comorbidities in patients with COVID-19 with a share of 20%. Diabetes mellitus in patients most often occurs in combination with cardiovascular diseases and arterial hypertension (20.3% and 16.3%, respectively). Combination of diabetes mellitus, arterial hypertension and other diseases was detected in 72.4% of patients. Combination of diabetes mellitus, cardiovascular and other diseases was detected in 32.5%.
In diabetes mellitus patients, COVID-19 was more severe, the hospital stay was longer, and patients over 60 years of age suffered. These patients had a combination of diabetes mellitus with arterial hypertension, obesity, and cardiovascular diseases. Hyperglycemia, elevated blood pressure, rapid breathing, and low saturation were more common for these patients.
Conclusion: Diabetes mellitus ranks second in the structure of comorbidities in COVID-19 in the south region of Kazakhstan and is characterized by a combination with cardiovascular diseases, arterial hypertension and obesity. In patients with diabetes, COVID-19 is more severe, which affects the length of stay in the hospital, the mortality rate and the need for transfer to the Intensive Care Unit.
Keywords: Pandemic, COVID-19, diabetes mellitus, comorbidities

CITATION

Abilbayeva A, Tarabayeva A, Idrisova G, Abdrakhmanova A, Sadykova A, Yegemberdiyeva R, et al. Clinical and laboratory COVID-19 features in hospitalized patients with concomitant diabetes mellitus type 2: A retrospective study. J CLIN MED KAZ. 2022;19(6):83-8. https://doi.org/10.23950/jcmk/12719

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