Development of adoptive immunotherapy technology in post-transplantation period
Освоение технологии адоптивной иммунотерапии в пост трансплантационный период.
Yuriy Kim 1, Samat Saparbayev 1, Bolatbek Kayupov 1, Zhuldyzay Kassymova 1, Aynara Darbayeva 1
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1 Center for cell technology and transplantation National Scientific Medical Research Center, Astana city, Kazakhstan
J CLIN MED KAZ, Volume 2, Issue 32, pp. 73-75.
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ABSTRACT
After liver transplantation due to recurrent HCV infection, recurrence of hepatocellular carcinoma is common. It leads to graft loss and patient’s death. Adoptive immunotherapy based on natural killers has huge potential in prevention of hepatitis C recurrence and subsequent hepatocellular carcinoma development.
CITATION
Kim Y, Saparbayev S, Kayupov B, Kassymova Z, Darbayeva A. Development of adoptive immunotherapy technology in post-transplantation period. Journal of Clinical Medicine of Kazakhstan. 2014;2(32):73-5.
REFERENCES
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- Adoptive immunotherapy with liver allograft–derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice. Masahiro Ohira, Kohei Ishiyama, Yuka Tanaka, Marlen Doskali, Yuka Igarashi, Hirotaka Tashiro, Nobuhiko Hiraga, Michio Imamura, Naoya Sakamoto,Toshimasa Asahara, Kazuaki Chayama and Hideki Ohdan // J Clin Invest. 2009.-Vol.119(11).-P.3226–3235.