Follow-up of Neonatal Ovarian Cysts. A Retrospective Cross-sectional Study

Наблюдение за кистой яичника у новорожденных. Ретроспективное поперечное исследование
Didem Baskin Embleton 1 * , Betul Zengin 2, Ahmet Ali Tuncer 1, Ahmet Afşin Kundak 3, Evrim Ozkaraca Boyaci 1, Salih Çetinkurşun 1
More Detail
1 Department of Pediatric Surgery, Faculty of Medicine, Afyonkarahisar University of Health Sciences, Afyonkarahisar, Turkey
2 Department of Radiology, Faculty of Medicine, Afyonkarahisar University of Health Sciences, Afyonkarahisar, Turkey
3 Department of Neonatology, Faculty of Medicine, Afyonkarahisar University of Health Sciences, Afyonkarahisar, Turkey
* Corresponding Author
J CLIN MED KAZ, Volume 3, Issue 53, pp. 38-41. https://doi.org/10.23950/1812-2892-JCMK-00695
OPEN ACCESS 3090 Views 1922 Downloads
Download Full Text (PDF)

ABSTRACT

Objective: This study was planned to see the results of follow-up of ovarian cysts in newborn patients at a university hospital.
Methods: Newborns with ovarian cysts that were diagnosed by US between 2010 and 2018 were retrospectively evaluated. US follow-up was performed in 2 to 3 month periods. Initial largest diameter of the ovarian cyst, number of cysts, bilateral or unilateral localization, if the cyst is complex or simple, alpha fetoprotein and β-HCG levels, if operated the type of the operation and pathology results were retrieved.
Results: Nineteen patients were included. Seven patients had ovarian cysts ≥20 mm and 5 were complex cysts. Two of 5 complex cysts were operated for abdominal mass and ovarian torsion was diagnosed. Other 3 complex cysts are having a conservative treatment due to lack of any clinical symptoms. All regressed in size. All simple cysts had non-operative management and regressed in size during follow-up. AFP levels were high in all. Control AFP levels decreased in all patients.
Conclusion: Conservative management seems appropriate for patients both with complex or simple cysts, because nearly all cysts were regressed and both ovaries persisted during follow-up. Surgical decision was the clinical presence of a mass in complex cysts. This is a small series and follow-up is short to make a final decision for management. A consensus is needed among the surgeons about the treatment options after discussing the complications related to conservative and surgical approaches of complex ovarian cysts.
Keywords: infant, newborn, ovary, ovarian cysts

CITATION

Baskin Embleton D, Zengin B, Tuncer AA, Kundak AA, Ozkaraca Boyaci E, Çetinkurşun S. Follow-up of Neonatal Ovarian Cysts. A Retrospective Cross-sectional Study. Journal of Clinical Medicine of Kazakhstan. 2019;3(53):38-41. https://doi.org/10.23950/1812-2892-JCMK-00695

REFERENCES

  • Papic JC, Billmire DF, Rescorla FJ, Finnell SME, Leys CM. Management of neonatal ovarian cysts and its effect on ovarian preservation. J Pediatr Surg. 2014; 49:990-4. https://doi.org/10.1016/j.jpedsurg.2014.01.040
  • Cesca E, Midrio P, Boscolo-Berto R, Snijders D, Salvador L, D'Antona D et al. Conservative treatment for complex neonatal ovarian cysts: A long term follow-up analysis. J Pediatr Surg. 2013; 48:510-5. https://doi.org/10.1016/j.jpedsurg.2012.07.067
  • Cohen HL, Shapiro MA, Mandel FS, Shapiro ML. Normal ovaries in neonates and infants: A sonographic study of 77 patients 1 day to 24 months old. AJR Am J Roentgenol. 1993; 160:583-6. https://doi.org/10.2214/ajr.160.3.8430559
  • Akın MA, Akın L, Özbek S, Tireli G, Kavuncuoğlu S, Sander S et al. Fetal-neonatal ovarian cysts-their monitoring and management: Retrospective evaluation of 20 cases and review of the literature. J Clin Res Pediatr Endocrinol. 2010; 2:28-33. https://doi.org/10.4274/jcrpe.v2i1.28
  • La Rosa C, Traggiai C, Stanhope R. Normal Childhood, puberty and adolescence. In: Balen AH, Creighton SM, Davies MC, MacDuogall J, Stanhope R, eds. Paediatric and Adolescent Gynaecolgy, A Multidisciplinary Approach. 1st ed. Cambridge: Cambridge University Press. 2004; 44-50. https://doi.org/10.1017/CBO9780511527036.005
  • Hannah Peters. The development and maturation of the ovary. Annales de Biologie animale, biochimie, biophysique. 1976; 16:271-8. https://doi.org/10.1051/rnd:19760301
  • Mizuno M, Kato T, Hebiguchi T, Yoshino H. Surgical indications for neonatal ovarian cysts. Tohoku J Exp Med. 1998; 186:27-32. https://doi.org/10.1620/tjem.186.27
  • Chiaramonte C, Piscopo A, Cataliotti F. Ovarian cysts in newborns. Pediatr Surg Int. 2001; 17:171-4. https://doi.org/10.1007/s003830000471
  • Servaes S, Zurakowski D, Laufer MR, Feins N, Chow JS. Sonographic findings of ovarian torsion in children. Pediatr Radiol. 2007; 37:446-51. https://doi.org/10.1007/s00247-007-0429-x
  • Ozcan HN, Balci Ş, Ekinci S, Gunes A, Oguz B, Ciftci AO et al. Imaging findings of fetal-neonatal ovarian cysts complicated with ovarian torsion and autoamputation. AJR Am J Roentgenol. 2015; 205:185-9. https://doi.org/10.2214/AJR.14.13426
  • Monnery-Noché ME, Auber F, Jouannic JM, Bénifla JL, Carbonne B, Dommergues M et al. Fetal and neonatal ovarian cysts: is surgery indicated? Prenat Diagn. 2008; 28:15-20. https://doi.org/10.1002/pd.1915
  • Ushakov FB, Meirow D, Prus D, Libson E, BenShushan A, Rojansky N. Parasitic ovarian dermoid tumor of the omentum-A review of the literature and report of two new cases. Eur J Obstet Gynecol Reprod Biol. 1998; 81:77-82. https://doi.org/10.1016/S0301-2115(98)00144-4
  • U.S. Department of Health and Human Services (Internet). Available from: https://www.fda.gov/Drugs/DrugSafety/ucm554634.htm