Giant Frontal Sinus Osteoma Presenting as Abducens Nerve Palsy with a Local Granulomatous Inflammation: Case Report with a Literature Review

Aidos Moldabekov 1, Aiman Maidan 1 * , Didar Zeitkaziyeva 2, Murat Talasbayev 3, Elvira Kadraliyeva 4, Kanat Akhmetov 3, Nurzhan Ryskeldiyev 1, Serik Akshulakov 1
More Detail
1 Department of Brain Neurosurgery, National Centre for Neurosurgery, Astana, Kazakhstan
2 Nazarbayev University School of Medicine, Nazarbayev University, Astana, Kazakhstan
3 Neurosurgery Department, Multidisciplinary City Hospital No1, Astana, Kazakhstan
4 Department of Eye disease, Astana Medical Univrsity, Astana, Kazakhstan
* Corresponding Author
J CLIN MED KAZ, Volume 21, Issue 4, pp. 74-77. https://doi.org/10.23950/jcmk/14963
OPEN ACCESS 438 Views 252 Downloads
Download Full Text (PDF)
Author Contributions: Conceptualization, M.A. and M.A.; methodology, Z.D. and T.M.; validation, Z.D. and T.M.; formal analysis, Z.D. and M.A.; investigation, Z.D. and M.A.; resources, Z.D. and M.A.; data curation, K.E. and A.K.; writing – original draft preparation, Z.D. and M.A.; writing – review and editing, M.A. and M.A.;  visualization, M.A. and M.A.; supervision, R.N. and A.S.; project administration, R.N. and A.S.; funding acquisition, Z.D. and T.M. All authors have read and agreed to the published version of the manuscript.

Informed Consent: Written informed consent was obtained from the patient for the publication of this case report and the accompanying images. A copy of the written consent is available for review by the editorial office of this journal.

Ethic approval and consent to participate: The photographs are completely unidentified and personal details are not mentioned in the text. The authors are accountable for all aspects of the work and for ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

ABSTRACT

Osteoma is one of the rare benign bone tumors and often presented asymptomatic through which could be expanded to close tissues. The current article will present a case report of giant frontal sinus osteoma and successful surgical treatment. The described tumor's size is astounding and among one of the biggest currently reported. In a discussion section, we try to provide the helpful groundwork for this disease’s etiology and describe the surgical approach performed. The purpose of this study is to present the clinical symptoms, radiological findings, and surgical indications of a giant frontal sinus osteoma with an orbital cavity expansion and secondary VI cranial nerve palsy. Moreover, histological findings of the tumor in the forms of granulomatous inflammation and tumor-infiltrating lymphocytes with single multinucleated giant cells brought our attention to provide additional antibacterial treatment and perform an osteoplastic operation 6 months later.
Keywords: giant osteoma, local inflammation, osteoplasty

CITATION

Moldabekov A, Maidan A, Zeitkaziyeva D, Talasbayev M, Kadraliyeva E, Akhmetov K, et al. Giant Frontal Sinus Osteoma Presenting as Abducens Nerve Palsy with a Local Granulomatous Inflammation: Case Report with a Literature Review. J CLIN MED KAZ. 2024;21(4):74-7. https://doi.org/10.23950/jcmk/14963

REFERENCES

  • McHugh JB, Mukherji SK, Lucas DR. Sino-orbital osteoma: a clinicopathologic study of 45 surgically treated cases with emphasis on tumors with osteoblastoma-like features. Archives of pathology & laboratory medicine. 2009; 133(10): 1587–1593. https://doi.org/10.5858/133.10.1587.
  • Serinelli S, de la Roza G. Osteoma, NOS. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/boneosteoma.html. Accessed June 16th, 2023.
  • Watley DC, Mong ER, Rana NA, Illing EA, Chaaban MR. Surgical Approach to Frontal Sinus Osteoma: A Systematic Review. Am J Rhinol Allergy. 2019; 33(5): 462–469. https://doi.org/10.1177/1945892419839895
  • Kakkar A, Nambirajan A, Suri V, Sarkar C, Kale SS, Singh M, Sharma MC. Primary Bone Tumors of the Skull: Spectrum of 125 Cases, with Review of Literature. J Neurol Surg B Skull Base. 2016; 77(4): 319–325. https://doi.org/10.1055/s-0035-1570347.
  • Haddad FS, Haddad GF, Zaatari G. Cranial osteomas: their classification and management. Report on a giant osteoma and review of the literature. Surg Neurol. 1997; 48(2): 143–147. https://doi.org/10.1016/S0090-3019(96)00485-5.
  • Sendul SY, Mavi Yildiz A, Yildiz AA. Giant osteomas: Clinical results and surgical approach from ophthalmic point of view. Eur J Ophthalmol. 2021; 31(2): 766–773. https://doi.org/10.1177/1120672120962041.
  • Palazzolo V, Tronchet A, Valsecchi S, Bellocchi S, Gervasoni C, Spotti S, Francesco AD, Colombo L, Riccio S, Ronchi P. Removal of a Frontal Sinus Osteoma and Reconstruction by a Custom-Made Implant with Neuronavigation Assistance. Craniomaxillofac Trauma Reconstr. 2018; 11(4): 305–313. https://doi.org/10.1055/s-0037-1607066.
  • Dispenza C, Martines F, Dispenza F, Caramanna C, Saraniti C. Frontal sinus osteoma complicated by palpebral abscess: case report. Acta Otorhinolaryngol Ital. 2004; 24(6): 357–360.
  • Licci M, Zweifel C, Hench J, Guzman R, Soleman J. Frontoethmoidal Osteoma with Secondary Intradural Mucocele Extension Causing Frontal Lobe Syndrome and Pneumocephalus: Case Report and Review of Literature. World Neurosurgery. 2018; 115: 301–308. https://doi.org/10.1016/j.wneu.2018.04.071.
  • Cheng KJ, Wang SQ, Lin L. Giant osteomas of the ethmoid and frontal sinuses: Clinical characteristics and review of the literature. Oncol Lett. 2013; 5(5): 1724–1730. https://doi.org/10.3892/ol.2013.1239.