Hairy Cell Leukemia with Unusual Clinical Presentations: A Single Center Experience

Волосатоклеточный лейкоз с необычными клиническими проявлениями: опыт одного центра
Abdulkadir Basturk 1, Sema Akinci 1, Tuba Hacibekiroglu 1, Tekin Guney 1, Sule MB Ozturk 1, Ali Kutlucan 2, Imdat Dilek 1
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1 Ataturk Research and Training Hospital, Ankara, Turkey
2 Selcuklu University, Konya, Turkey
J CLIN MED KAZ, Volume 1, Issue 35, pp. 55-58.
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ABSTRACT

Objective: In this study we report 10 cases of hairy cell leukemias (HCL). Some of them were presented with atypical and rare clinical presentations: One of them was presented with ascites, another case was presented with intramuscular hematoma and four cases were presented with no splenomegaly.
Material and Methods: From 2009 to 2013, HCL diagnosed in 10 of 186 (%5.3) acute and chronic leukemias and they were included in this study.
Results and conclusion: In a total of 10 cases (female:4 male:6) mean age was 60,2 (range 31-85). Splenomegaly was not present in four cases (40%), pancytopenia was not present in three cases (30%). One case was presented with ascites. Another case was presented with intramuscular hematoma. Eigth patients were treated with cladribin with 87,5% complete response and 12,5% partial response rate. One patient was treated only with palliative radiotherapy. One patient was treated in another hospital after diagnosis.
Keywords: Hairy cell leukemia, lymphoproliferative disorder, ascites, atypical presentation

CITATION

Basturk A, Akinci S, Hacibekiroglu T, Guney T, Ozturk SM, Kutlucan A, et al. Hairy Cell Leukemia with Unusual Clinical Presentations: A Single Center Experience. Journal of Clinical Medicine of Kazakhstan. 2015;1(35):55-8.

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