Informant-based questionnaire for early detection of cognitive disorders in the olders in Kazakhstan

Assel Tukinova 1 * , Gulnar Shalgumbayeva 2, Zhanna Mussabekova 2
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1 Department of Public Health, Semey Medical University, Semey, Kazakhstan
2 Department of Family Medicine, Semey Medical University, Semey, Kazakhstan
* Corresponding Author
J CLIN MED KAZ, Volume 19, Issue 3, pp. 24-27. https://doi.org/10.23950/jcmk/12108
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ABSTRACT

Aim: The purpose of this study was to identify cognitive disorders in older people by conducting a survey of their relatives (close people) by the Arizona Questionnaire.
Material and methods: The study involved people who had relatives (close ones) aged 60-74 years old. Three hundred and eighty respondents took part in the survey.
Results: Summing up all the points obtained during the survey of relatives 4-13 points 78.7% (n=299), which may indicate the presence of moderate cognitive disorders that are better not to be ignored (suggests going to the doctor) and above 13 points 6% (n=23) indicates a fairly high probability of dementia (urgent need to seek medical help). Our study revealed that family status (p<0.001), employment (p=0.014), and recitation of namaz (p=0.009) act as protective factors that promote social participation and build cognitive reserve. Social isolation, on the other hand, can lead to apathy, withdrawal, depression, and a greater likelihood of cognitive impairment. We also found that place of residence (p<0.001) and living conditions (p=0.002), may also influence the early formation of cognitive dysfunctions. Arizona Questionnaire has high sensitivity and specificity in detecting both mild cognitive impairments and Alzheimer's disease and allows clinicians to quickly and accurately assess people with reported cognitive problems.
Conclusion: As a result of survey informants, it was revealed that most of the olders, whose relatives have been surveyed, may be at risk of cognitive impairment and further testing is needed.
Keywords: informant, early detection, cognitive impairments

CITATION

Tukinova A, Shalgumbayeva G, Mussabekova Z. Informant-based questionnaire for early detection of cognitive disorders in the olders in Kazakhstan. J CLIN MED KAZ. 2022;19(3):24-7. https://doi.org/10.23950/jcmk/12108

REFERENCES

  • Jorm AF. The informant questionnaire on cognitive decline in the elderly (IQCODE): a review. Int Psychogeriatr. 2004;16(3):275–293. https://doi.org/10.1017/s1041610204000390
  • Jorm AF, Christensen H, Korten AE, Jacomb PA, Henderson AS. Informant ratings of cognitive decline in old age: validation against change on cognitive tests over 7 to 8 years. Psychol Med. 2000;30(4):981–985. https://doi.org/10.1017/s0033291799002299
  • Sabbagh MN, Malek-Ahmadi M, Belden CM. The use of informant-based questionnaires in differentiating mild cognitive impairment from normal aging. Expert Rev Neurother. 2012;12(6):637-9. https://doi.org/10.1586/ern.12.45
  • Harrison JK, Fearon P, Noel-Storr AH, McShane R, Stott DJ, Quinn TJ. Informant questionnaire on cognitive decline in the elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting. The Cochrane database of systematic reviews 2014;7: CD010771. https://doi.org/10.1002/14651858.CD010771.pub2
  • Malek-Ahmadi M, Davis K, Belden C, Laizure B, Jacobson S, Yaari R, et al. Validation and diagnostic accuracy of the Alzheimer’s questionnaire. Age and Ageing. 2012;41(3):396–399. https://doi.org/10.1093/ageing/afs008
  • Budolfson K, Malek-Ahmadi M, Belden CM, Powell J, Davis K, Jacobson S, Sabbagh MN. Neuropsychological Correlates of the Alzheimer's Questionnaire. J Alzheimers Dis. 2015;46(2):389-97. https://doi.org/10.3233/JAD-142388
  • Malek-Ahmadi M, Sabbagh MN. Development and Validation of the Alzheimer's Questionnaire (AQ). J Nat Sci. 2015;1(5):e104.
  • Malek-Ahmadi M, Chen K, Davis K, Belden CM, Powell J, Jacobson SA, Sabbagh MN. Sensitivity to change and prediction of global change for the Alzheimer's Questionnaire. Alzheimers Res Ther. 2015;7:1. https://doi.org/10.1186/s13195-014-0092-z
  • Malek-Ahmadi M, Davis K, Belden CM, Sabbagh MN. Comparative analysis of the Alzheimer questionnaire (AQ) with the CDR sum of boxes, MoCA, and MMSE. Alzheimer Dis Assoc Disord. 2014;28(3):296-8. https://doi.org/10.1097/WAD.0b013e3182769731
  • Sabbagh MN, Malek-Ahmadi M, Kataria R, Belden CM, Connor DJ, Pearson C, et al. The Alzheimer’s questionnaire: a proof of concept study for a new informant-based dementia assessment. J Alzheimers Dis.2010;22(3):1015–1021. https://doi.org/10.3233/JAD-2010-101185
  • Li F, Jia X-F, Jia J. The Informant Questionnaire on Cognitive Decline in the Elderly individuals in screening mild cognitive impairment with or without functional impairment. J Geriatr Psychiatry Neurol. 2012;25(4):227-232. https://doi.org/10.1177/0891988712464822
  • Malek-Ahmadi M, Davis K, Belden CM, Jacobson S, Sabbagh MN. Informant-reported cognitive symptoms that predict amnestic mild cognitive impairment. BMC Geriatr. 2012;12:3. https://doi.org/10.1186/1471-2318-12-3
  • Chio O.I., Yip P-K., Liu Y-C., Chen L-H , Wang P-Ch, Tsai T-H, et al. Detection of cognitive impairment using self-rated AD8 and informant-reported AD8. J Formos Med Assoc. 2018;117(1):42-47. https://doi.org/10.1016/j.jfma.2017.02.0152018
  • Tukinova A, Shalgumbayeva GM, Mussabekova ZhA, Abzalova RA. Аwareness of Medical Workers with Early Diagnosis of Cognitive Disorders at the Primary Health Care Level in the Republic of Kazakhstan. Open Access Maced J Med Sci. 2020;8(E):595-600. https://doi.org/10.3889/oamjms.2020.5282
  • Perroco TR, Damin AE, Frota NA, Silva M-NM, Rossi V, Nitrini R, et al. Short IQCODE as a screening tool for MCI and dementia: Preliminary results. Dementia & neuropsychologia. 2008; 2(4):300–304. https://doi.org/10.1590/S1980-57642009DN20400012
  • Dong Y, Cheng TS, Tsou KY, Chan QL, Chen CL-H. Feasibility and acceptability of the informant AD8 for cognitive screening in primary healthcare: a pilot study. ScientificWorldJournal. 2014;302834. https://doi.org/10.1155/2014/302834
  • Maki Y, Yamaguchi T, Yamaguchi H. Symptoms of Early Dementia-11 Questionnaire (SED-11Q): A Brief Informant-Operated Screening for Dementia. Dement Geriatr Cogn Disord Extra. 2013;3:131-142. https://doi.org/10.1159/000350460