The comparison of risk factor between the young adult and elderly onset of ischemic stroke
Сравнение факторов риска у молодых и пожилых людей при наступлении ишемического инсульта
Rizaldy Taslim Pinzon 1, Fransiscus Buwana 1
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1 School of Medicine, Duta Wacana Christian University, Yogyakarta, Indonesia
J CLIN MED KAZ, Volume 2, Issue 48, pp. 28-32.
https://doi.org/10.23950/1812-2892-JCMK-00545
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ABSTRACT
Background: Young adults are likely to distinguish risk factor from elderly concerning ischemic stroke.
Aims and Objective: Measure the comparison of risk factor between the young adult and elderly onset of ischemic stroke.
Material and Methods: This was a cross sectional study using secondary data from electronic medical record and electronic stroke registry of Bethesda Hospital Yogyakarta Indonesia. The stroke was diagnosed with standard way by well-trained neurologist and confirmed with CT Scan. The risk factors were defined systematically. We used OpenEpi sample size calculation and Statistical Package for Social Sciences version 20 with significance level 0,05.
Results: The data of 200 subjects consisted of 100 patients aged under 50 years and 100 patients aged above 50 years. Patients in the elderly group more frequently had atrial fibrillation (92,3% vs 7,6%, p= 0.001). On the other hand, the elderly group more often dyslipidemia (52,1% vs 47,9%) and ischemic heart disease (75% vs 25%). Diabetes and hypertension are more common in young onset compare the old one (57,1% vs 42,9% and 57,6% vs 42,4%). There was not a significantly different risk’s factor include dyslipidemia, ischemic heart disease, diabetes and hypertension both of the group.
Conclusion: Atrial fibrillation is the leading risk factor for ischemic stroke, particularly in elderly patients. These findings suggest specializing stroke care to secondary prevention in patient with risk factors.
REFERENCES
- Chin JH and Vora N. The global burden of neurologic diseases. Neurology. 2014;83(4): 349–351.
- Kusuma Y, Venketasubramania N, Kiemas LS, and Misbach J. Burden of stroke in Indonesia. World Stroke Organization International Journal of Stroke. 2009;4:379–380.
- Rao C, Soemantri S, Djaja S, Suhardi, Adair T, Pangaribuan L, et al. Mortality in Central Java: results from The Indonesian mortality registration System strengthening Prospect. BMC Res Notes. 2010;3:325.
- Kuptniratsaikul V, Kovindha A, Suethanapornkul S, Manimmanakorn N and Archongka Y. Long-term morbidities in stroke survivors: a prospective multicenter study of Thai stroke rehabilitation registry. BMC Geriatrics.2013;13:33.
- Maaijwee NA, Rutten-Jacobs LC, Schaapsmeerders P, et al. Ischaemic stroke in young adults: risk factors and long-term consequences.Nat Rev Neurol. 2014; 10(6): 315–25.
- Béjot Y, Daubail B, Jacquin A, Durier J, Osseby GV, Rouaud O, Giroud M. Trends in the incidence of ischaemic stroke in young adults between 1985 and 2011: the Dijon Stroke Registry. J Neurol Neurosurg Psychiatry. 2014;85:509–513
- Radhakrishnan K, Ashok PP, Sridharan R et al. Stroke in the young: incidence and pattern in Benghazi, Libya. Acta Neurol Scand. 1986;73(4): 434–8.
- Morikawa Y, Nakagawa H, Naruse Y et al. Trends in stroke incidence and acute case fatality in a Japanese rural area: the Oyabe study. Stroke.2000; 31(7): 1583–7.
- Jacobs BS, Boden-Albala B, Lin IF, et al. Stroke in the young in the northern Manhattan stroke study. Stroke. 2002; 33(12): 2789–93.
- Smajlović D. Strokes in young adults: epidemiology and Prevention. Vascular Health and Risk Management 2015;11:157–164.
- Smajlović DŽ, Salihović D, Ibrahimagić OĆ, Sinanović O. Characteristics of stroke in young adults in Tuzla Canton, Bosnia and Herzegovina. Coll Antropol. 2013;37:515–519.
- Shimizu H, Kawarai T, Saji N et al. Re-evaluation of Clinical Features and Risk Factors of Acute Ischemic Stroke in Japanese Longevity Society. Kobe J. Med. Sci.2009. Vol.55, No. 6, pp. E132-E139
- Auriel E, Gur AY, Uralev O, Brill S, et al. Characteristics of first ever ischemic stroke in the very elderly: profile of vascular risk factors and clinical outcome. Clin Neurol Neurosurg 2011 113(8):654-7.
- Mirza M, Strunets A, Shen W, Jahangir A. Mechanisms of Arrhythmias and Conduction Disorders in Older Adults;2012 28(4): 555–573.
- Arboix, M. Miguel, E. C´ıscar, L. Garc´ıa-Eroles, J. Massons, and M. Balcells, “Cardiovascular risk factors in patients aged 85 or older with ischemic stroke,” Clinical Neurology and Neurosurgery, 2006.vol. 108, no. 7, pp. 638–643.
- R. Sankaranarayanan, G. Kirkwood, K. Dibb, C.J. Garratt, Comparison of atrial fibrillation in the young versus that in the elderly: a review, Cardiol. Res. Pract. 2013(2013) 976976
- Allard J. Hauer, Ynte M. Ruigrok, Ale Algra, Ewoud J. van Dijk, Peter J. Koudstaal,Gert-Jan Luijckx. Age-Specific Vascular Risk Factor Profiles According to Stroke Subtype. J Am Heart Assoc. 2017;6.
- Milionis HJ, Liberopoulos E, Goudevenos J, Bairaktari ET, Seferiadis K, Elisaf MS. Risk factors for first-ever acute ischemic non-embolic stroke in elderly individuals. nt J Cardiol. 2005 Mar 18;99(2):269-75
- Streja Dan. Management of Dyslipidemia in the Elderly. https://www.ncbi.nlm.nih.gov/books/NBK279133/ (assessed April 30, 2018).
- Zhang YN, He L. Risk factors study of ischemic stroke in young adults in Southwest China. Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 Jul;43(4):553-7
- Wu TY, Kumar A, Wong EH.Young ischaemic stroke in South Auckland: a hospital-based study. N Z Med J. 2012 Oct 26;125(1364):47-56.
- Xiao-ying Yao, Yan Lin, Jie-li Geng, Ya-meng Sun,Ying Chen, Guo-wen Shi, Qun Xu, and Yan-sheng Li . Age- and GenderSpecific Prevalence of Risk Factors in Patients with First-Ever Ischemic Stroke in China. Stroke Research and Treatment 2012
- Steg PG, Bhatt DL, Wilson PW, et al. One-year cardiovascular event rates in outpatients with atherothrombosis. JAMA 2007;297:1197-1206.
- Bettina VS, Jukka P, Ulrike G, Beate G, Ulf S. Lifestyle Risk Factors for Ischemic Stroke and Transient Ischemic Attack in Young Adults in the Stroke in Young Fabry Patients Study. Stroke. 2013;44:119-125
- Fromm A, Waje-Andreassen U, Thomassen L, et al. Comparison between Ischemic stroke patients <50 years and 50 years admitted to a single centre: TheBergen Stroke Study. Stroke Res Treat 2011; 2011: 183256.
- Von Sarnowski B, Putaala J, Grittner U, et al. Lifestyle risk factors for ischemic stroke and transient ischemic attack in young adults in the Stroke in Young Fabry Patients study. Stroke 2013; 44: 119–125.
- Rohr J, Kittner S, Feeser B, et al. Traditional risk factors and ischemic stroke in young adults: the Baltimore-Washington Cooperative Young Stroke Study.Arch Neurol 1996; 53: 603–607.
- Khoury JC, Kleindorfer D, Alwell K, et al. Diabetes mellitus: a risk factor for ischemic stroke in a large biracial population. Stroke. 2013; 44:1500–1504.