The frequency of hypernatremia at presenting to the Emergency Department with acute bronchiolitis

Dilek Konuksever 1 * , Eylem Gül Ateş 2
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1 Department of Pediatrics, Ankara City Hospital, Turkish Ministry of Health, Bilkent, Ankara, Turkey
2 Institutional Big Data Management Coordination Office, Middle East Technical University, Ankara, Turkey
* Corresponding Author
J CLIN MED KAZ, Volume 20, Issue 5, pp. 55-59. https://doi.org/10.23950/jcmk/13763
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ABSTRACT

Aim: Acute bronchiolitis is a common lower respiratory tract disease in children. In addition to its common clinical findings, it may also cause extrarenal water losses. Deficiency in total body water is a risk for hypernatremia. This study aimed to analyze the frequency of concomitant hypernatremia in children suffering from acute bronchiolitis.
Material and methods: This retrospective study was conducted with 1317 children who presented to the pediatric emergency department with acute bronchiolitis and whose sodium levels were measured from January 1, 2019, to March 1, 2020. The age, gender, and application season of the patients were recorded.
Results: Hypernatremia was detected in 193 (14.7%) patients, and hyponatremia was detected in 99 (7.5%). There was no statistical difference in age or gender between the hyponatremia, hypernatremia, and normonatremia groups (p>0.05). The frequency of hypernatremia was the highest in winter and spring (p<0.05).
Conclusion: Patients with acute bronchiolitis may be accompanied not only by hyponatremia but also by hypernatremia. To prevent dysnatremia in patients with acute bronchiolitis, each child's intravenous hydration regimen must be ordered to electrolyte levels.

CITATION

Konuksever D, Gül Ateş E. The frequency of hypernatremia at presenting to the Emergency Department with acute bronchiolitis. J CLIN MED KAZ. 2023;20(5):55-9. https://doi.org/10.23950/jcmk/13763

REFERENCES

  • Narchi H. Hypernatremia in children. Journal of Pediatric Biochemistry. 2013;3(04):213-24. https://doi.org/10.1055/s-0036-1586449
  • Kamel KS, Schreiber M, Harel Z. Hypernatremia. JAMA. 2022;327(8):774-5. https://doi.org/10.1001/jama.2022.1376
  • Liamis G, Filippatos TD, Elisaf MS. Evaluation and treatment of hypernatremia: a practical guide for physicians. Postgraduate medicine. 2016;128(3):299-306. https://doi.org/10.1080/00325481.2016.1147322
  • Yun G, Baek SH, Kim S. Evaluation and management of hypernatremia in adults: clinical perspectives. The Korean Journal of Internal Medicine. 2022.
  • Lavagno C, Milani GP, Uestuener P, Simonetti GD, Casaulta C, Bianchetti MG, et al. Hyponatremia in children with acute respiratory infections: a reappraisal. Pediatric pulmonology. 2017;52(7):962-7. https://doi.org/10.1002/ppul.23671
  • Shein SL, Slain K, Martinez Schlurmann N, Speicher R, Rotta AT. Hyponatremia and hypotonic intravenous fluids are associated with unfavorable outcomes of bronchiolitis admissions. Hospital pediatrics. 2017;7(5):263-70. https://doi.org/10.1542/hpeds.2016-0205
  • Milani GP, Rocchi A, Teatini T, Bianchetti MG, Amelio G, Mirra N, et al. Hyponatremia in infants with new onset moderate-severe bronchiolitis: A cross-sectional study. Respiratory Medicine. 2017;133:48-50. https://doi.org/10.1016/j.rmed.2017.10.028
  • Mhatre SS, Kumbhar SG. Study of hyponatremia in paediatric patients with acute lower respiratory tract infection. Journal of Evolution of Medical and Dental Sciences. 2019;8(21):1704-8. https://doi.org/10.14260/jemds/2019/375
  • Elamin A, Nair P. Hypernatremic dehydration in infancy. Sudanese Journal of Paediatrics. 2020;8(1):161-.
  • Bataille S, Baralla C, Torro D, Buffat C, Berland Y, Alazia M, et al. Undercorrection of hypernatremia is frequent and associated with mortality. BMC nephrology. 2014;15(1):1-9. https://doi.org/10.1186/1471-2369-15-37
  • Zheng F, Ye X, Shi X, Lin Z, Yang Z, Jiang L. Hyponatremia in children with bacterial meningitis. Frontiers in neurology. 2019;10:421. https://doi.org/10.3389/fneur.2019.00421
  • Anigilaje EA. Management of diarrhoeal dehydration in childhood: A review for clinicians in developing countries. Frontiers in pediatrics. 2018;6:28. https://doi.org/10.3389/fped.2018.00028
  • Daly K, Farrington E. Hypokalemia and hyperkalemia in infants and children: pathophysiology and treatment. Journal of Pediatric Health Care. 2013;27(6):486-96. https://doi.org/10.1016/j.pedhc.2013.08.003
  • Yeter HH, Korucu B, Akcay OF, Derici K, Derici U, Arinsoy T. Effects of medium cut-off dialysis membranes on inflammation and oxidative stress in patients on maintenance hemodialysis. International Urology and Nephrology. 2020;52:1779-89. https://doi.org/10.1007/s11255-020-02562-3
  • Lindner G, Funk G-C. Hypernatremia in critically ill patients. Journal of critical care. 2013;28(2):216. e11-. e20. https://doi.org/10.1016/j.jcrc.2012.05.001
  • Patel N, Patel D, Farouk SS, Rein JL. Salt and Water: A Review of Hypernatremia. Advances in Kidney Disease and Health. 2023;30(2):102-9. https://doi.org/10.1053/j.akdh.2022.12.010
  • Ranjan R, Lo SC-Y, Ly S, Krishnananthan V, Lim AK. Progression to severe hypernatremia in hospitalized general medicine inpatients: an observational study of hospital-acquired hypernatremia. Medicina. 2020;56(7):358. https://doi.org/10.3390/medicina56070358
  • Zieg J. Diagnosis and management of hypernatraemia in children. Acta Paediatrica. 2022;111(3):505-10. https://doi.org/10.1111/apa.16170
  • Imai N, Sumi H, Shibagaki Y. Impact of age on the seasonal prevalence of hypernatremia in the emergency department: a single-center study. International Journal of Emergency Medicine. 2019;12:1-4. https://doi.org/10.1186/s12245-019-0246-7