The predictive value of the prognostic nutritional index for contrast-induced nephropathy

Murat Gucun 1, Serkan Senger 2, Muzaffer Kahyaoğlu 3 * , Okan Akyuz 1, Mehmet Celik 4, Ahmet Guner 5, Yusuf Yilmaz 6
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1 Department of Nephrology, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey
2 Department of General Surgery, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey
3 Department of Cardiology, Beykoz State Hospital, Istanbul, Turkey
4 Department of Cardiology, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey
5 Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Istanbul , Turkey
6 Department of Cardiology, Goztepe Training and Research Hospital, Istanbul, Turkey
* Corresponding Author
J CLIN MED KAZ, Volume 19, Issue 1, pp. 46-49. https://doi.org/10.23950/jcmk/11585
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ABSTRACT

Aim: This study aims to evaluate the association between prognostic nutritional index (PNI) and contrast-induced nephropathy (CIN).
Material and methods: A total of 251 patients who were at high risk for contrast nephropathy were included in the study. The patients were grouped according to their PNI score (PNI score <45 or PNI score ≥45). CIN was defined as a 25% relative increase, or 0.5 mg/dL absolute increase in serum creatinine level above baseline within 72 hours of contrast exposure, in the absence of an alternative explanation.
Results: Two groups were assigned according to the PNI score. The first group consists of 111 patients (PNI<45) and the second group has 140 patients (PNI≥45). CIN developed in 162 (%64.8) patients. C-reactive protein was higher in the low-PNI group. Also, the patients with the low-PNI group had lower ejection fraction, lower serum albumin levels, and lower hemoglobin levels. CIN, postprocedure renal replacement therapy requirement and in-hospital mortality were higher in the low PNI group.  Multivariable logistic regression analysis revealed that advanced age (p=0.012, [OR] = 1.044 [1.009-1.079]), low baseline GFR (p=0.033, [OR]= 1.022 [1.002-1.043]), high amount of contrast media (p=0.022, [OR]= 1.017 [1.002-1.031]), and low PNI score (p=0.033 , [OR]= 2.069 [1.060-4.039]) were independent predictors of CIN.
Conclusion: Our study demonstrated that the PNI score was an independent risk factor for the development of CIN.
Keywords: prognostic nutritional index, contrast induced nephropathy, coronary angiography, percutaneous coronary intervention

CITATION

Gucun M, Senger S, Kahyaoğlu M, Akyuz O, Celik M, Guner A, et al. The predictive value of the prognostic nutritional index for contrast-induced nephropathy. J CLIN MED KAZ. 2022;19(1):46-9. https://doi.org/10.23950/jcmk/11585

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