The role of neutrophilic extracellular traps in oncogenesis

Роль нейтрофильных внеклеточных ловушек в онкогенезе
Mereke Maratkyzy 1 * , Aruna Kosybaeva 2, Naylya Kabildina 1, Anelya Beisenaeva 1
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1 Oncology and Radiodiagnosis Department, Karaganda Medical University, Karaganda, Republic of Kazakhstan
2 No3 Department of Internal Medicine, Karaganda Medical University, Karaganda, Republic of Kazakhstan
* Corresponding Author
J CLIN MED KAZ, Volume 1, Issue 51, pp. 16-20. https://doi.org/10.23950/1812-2892-JCMK-00664
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ABSTRACT

Views on the role of extracellular neutrophilic traps in oncology vary greatly. On the one hand, there is evidence of the anticarcinogenic properties of neutrophil networks associated with the direct destruction of tumor cells and stimulation of the immune system. Cytotoxicity towards tumor cells is manifested by trap components (myeloperoxidase, proteinases and histones), while DNA strands are considered as a kind of tool for capturing tumor cells and limiting their further spread.
Keywords: extracellular neutrophilic traps, oncology, tumor

CITATION

Maratkyzy M, Kosybaeva A, Kabildina N, Beisenaeva A. The role of neutrophilic extracellular traps in oncogenesis. Journal of Clinical Medicine of Kazakhstan. 2019;1(51):16-20. https://doi.org/10.23950/1812-2892-JCMK-00664

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